Zoek op trefwoord in de betreffende kolom boven de tabel of gebruik het algemene zoekveld.
Rood: alternatief (dosis)advies beschikbaar. Farmacogenetica is zinvol / kan zinvol zijn. Neem contact op met de dienstdoende ziekenhuisapotheker (055-8446004).
Blauw: beperkte rol metabolisme, geen aangepaste dosis nodig of niet beoordeeld. Farmacogenetica is niet zinvol.
Zwart: geen aangepaste dosis nodig of niet beoordeeld. Farmacogenetica is niet zinvol.
| Naam | Groep | 1A2 | 2B6 | 2C9 | 2C19 | 2D6 | 3A4 | 3A5 | VKORC1 | DPD | TPMT | SLCO1B1 | UGT | ||||||||||||
| 5FU | Oncolytica | – | – | – | – | – | – | – | – | JA | – | – | – | ||||||||||||
| Acenocoumarol | Antitrombotica | JA | – | JA | – | – | – | – | JA | – | – | – | – | ||||||||||||
| Alfentanil | Analgetica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Alprazolam | Psychofarmaca | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Amfetamine | Drugs of abuse | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Amitriptyline | Psychofarmaca | JA | – | JA | JA | JA | – | – | – | – | – | – | – | ||||||||||||
| Amlodipine | RAAS-remmers | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Apixaban | Antitrombotica | – | – | – | – | – | JA | JA | – | – | – | – | – | ||||||||||||
| Aprepitant | Anti-emetica | JA | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Aripiprazol | Psychofarmaca | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Atazanavir | Antivirale middelen | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Atomoxetine | Psychofarmaca | – | – | – | JA | JA | – | – | – | – | – | – | – | ||||||||||||
| Atorvastatine | Antilipaemica | – | – | – | – | – | JA | – | – | – | – | JA | – | ||||||||||||
| Azathioprine | Immunomodulantia | – | – | – | – | – | – | – | – | – | JA | – | – | ||||||||||||
| Bisoprolol | Beta-blokkers | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Brexipiprazol | Psychofarmaca | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Brivaracetam | Anti-epileptica | – | – | – | JA | – | – | – | – | – | – | – | – | ||||||||||||
| Bupropion | Psychofarmaca | – | JA | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Buspiron | Psychofarmaca | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Cafeïne | Psychofarmaca | JA | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Capecitabine | Oncolytica | – | – | – | – | – | – | – | – | JA | – | – | – | ||||||||||||
| Carbamazepine | Anti-epileptica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Cariprazine | Psychofarmaca | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Carvedilol | Beta-blokkers | – | – | JA | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Celecoxib | Analgetica | – | – | JA | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Chlooramfenicol | Antimicrobiële middelen | – | – | – | JA | – | – | – | – | – | – | – | – | ||||||||||||
| Chloorpromazine | Anti-emetica | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Ciclosporine | Immunomodulantia | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Cisapride | Anti-emetica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Citalopram | Psychofarmaca | – | – | – | JA | JA | JA | – | – | – | – | – | – | ||||||||||||
| Claritromycine | Antimicrobiële middelen | – | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Clomipramine | Psychofarmaca | JA | – | – | JA | JA | JA | – | – | – | – | – | – | ||||||||||||
| Clopidogrel | Antitrombotica | – | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Clopentixol | Psychofarmaca | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Clozapine | Psychofarmaca | JA | – | – | JA | JA | JA | – | – | – | – | – | – | ||||||||||||
| Cocaïne | Drugs of abuse | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Codeïne | Analgetica | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Cyclofosfamide | Oncolytica | – | JA | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Dabigatran | Antitrombotica | – | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Dapson | Antimicrobiële middelen | – | – | JA | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Dexamethason | Corticosteroïden | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Dexamfetamine | Psychofarmaca | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Dextromethorfan | Hoestmiddelen | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Diazepam | Psychofarmaca | – | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Diltiazem | Calciumantagonisten | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Diclofenac | Analgetica | – | – | JA | – | – | – | – | – | – | – | – | – | ||||||||||||
| Docetaxel | Oncolytica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Domperidon | Anti-emetica | JA | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Donepezil | Para-sympathicomimetica | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Doxepine | Psychofarmaca | JA | – | – | JA | JA | JA | – | – | – | – | – | – | ||||||||||||
| Duloxetine | Psychofarmaca | JA | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Efavirenz | Antivirale middelen | – | JA | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Eliglustat | Middelen bij metabole aandoeningen | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Eplerenon | Diuretica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Erytromycine | Antimicrobiële middelen | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Escitalopram | Psychofarmaca | – | – | – | JA | JA | JA | – | – | – | – | – | – | ||||||||||||
| Esomeprazol | Maagzuurremmers | – | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Estradiol | Geslachtshormonen | JA | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Ethosuximide | Anti-epileptica | – | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Felbamaat | Anti-epileptica | – | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Felodipine | Calciumantagonisten | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Fenobarbital | Anti-epileptica | – | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Fentanyl | Analgetica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Fenprocoumon | Antitrombotica | – | – | JA | – | – | – | – | JA | – | – | – | – | ||||||||||||
| Fenytoïne | Anti-epileptica | – | – | JA | JA | – | – | – | – | – | – | – | – | ||||||||||||
| Finasteride | Urologische middelen | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Flecaïnide | Anti-aritmica | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Flucytosine | Antischimmel middelen | – | – | – | – | – | – | – | – | JA | – | – | – | ||||||||||||
| Flufenazine | Psychofarmaca | JA | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Fluoxetine | Psychofarmaca | – | – | JA | JA | JA | JA | JA | – | – | – | – | – | ||||||||||||
| Flupentixol | Psychofarmaca | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Fluvastatine | Antilipaemica | – | – | JA | JA | JA | JA | – | – | – | – | JA | – | ||||||||||||
| Fluvoxamine | Psychofarmaca | JA | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Gabapentine | Anti-epileptica | – | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Gefitinib | Oncolytica | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Glibenclamide | Bloedglucose verlagende middelen | – | – | JA | – | – | – | – | – | – | – | – | – | ||||||||||||
| Glimepiride | Bloedglucose verlagende middelen | – | – | JA | – | – | – | – | – | – | – | – | – | ||||||||||||
| Guanfacine | Psychofarmaca | – | – | – | – | – | JA | JA | – | – | – | – | – | ||||||||||||
| Haloperidol | Psychofarmaca | JA | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Hydrocortison | Corticosteroïden | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Ibuprofen | Analgetica | – | – | JA | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Ifosfamide | Oncolytica | – | JA | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Imatinib | Oncolytica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Imipramine | Psychofarmaca | JA | – | – | JA | JA | JA | – | – | – | – | – | – | ||||||||||||
| Indinavir | Antivirale middelen | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Indometacine | Analgetica | – | – | JA | JA | – | – | – | – | – | – | – | – | ||||||||||||
| Irbesartan | RAAS-remmers | – | – | JA | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Irinotecan | Oncolytica | – | – | – | – | – | JA | – | – | – | – | – | 1A1 | ||||||||||||
| Kinidine | Anti-aritmica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Lacosamide | Anti-epileptica | – | – | – | JA | – | – | – | – | – | – | – | – | ||||||||||||
| Lamotrigine | Anti-epileptica | – | – | – | – | – | – | – | – | – | – | – | 1A4 | ||||||||||||
| Lansoprazol | Maagzuurremmers | – | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Lercanidipine | Calciumantagonisten | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Lidocaïne | Anesthetica | JA | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Losartan | RAAS-remmers | – | – | JA | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Lovastatine | Antilipaemica | – | – | – | – | – | JA | – | – | – | – | JA | – | ||||||||||||
| Melatonine | Overig | JA | – | – | JA | – | – | – | – | – | – | – | – | ||||||||||||
| Meloxicam | Analgetica | – | – | JA | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Mercaptorpurine | Immunomodulantia | – | – | – | – | – | – | – | – | – | JA | – | – | ||||||||||||
| Methadon | Analgetica | – | JA | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Metoprolol | Beta-blokkers | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Midazolam | Psychofarmaca | – | – | – | – | – | JA | JA | – | – | – | – | – | ||||||||||||
| Mirtazapine | Psychofarmaca | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Moclobemide | Psychofarmaca | – | – | – | JA | JA | – | – | – | – | – | – | – | ||||||||||||
| Naproxen | Analgetica | JA | – | JA | – | – | – | – | – | – | – | – | – | ||||||||||||
| Nebivolol | Beta-blokkers | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Nifedipine | Calciumantagonisten | JA | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Nilotinib | Oncolytica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Nilutamide | Oncolytica | – | – | – | JA | – | – | – | – | – | – | – | – | ||||||||||||
| Nitrendipine | Calciumantagonisten | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Nortriptyline | Psychofarmaca | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Olanzapine | Psychofarmaca | JA | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Omeprazol | Maagzuurremmers | – | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Ondansetron | Anti-emetica | JA | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Oxcarbazepine | Anti-epileptica | – | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Oxycodon | Analgetica | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Pantoprazol | Maagzuurremmers | – | – | JA | JA | JA | JA | – | – | – | – | – | – | ||||||||||||
| Paracetamol | Analgetica | JA | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Paroxetine | Psychofarmaca | JA | – | – | JA | JA | JA | JA | – | – | – | – | – | ||||||||||||
| Perampanel | Anti-epileptica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Perfenazine | Psychofarmaca | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Pimozide | Psychofarmaca | JA | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Piroxicam | Analgetica | – | – | JA | – | – | – | – | – | – | – | – | – | ||||||||||||
| Prasugrel | Antitrombotica | – | JA | JA | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Pravastatine | Antilipaemica | – | – | – | – | – | – | – | – | – | – | JA | – | ||||||||||||
| Pregabaline | Anti-epileptica | – | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Primidon | Anti-epileptica | – | – | JA | – | – | – | – | – | – | – | – | – | ||||||||||||
| Progesteron | Geslachtshormonen | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Proguanil | Antiprotozoica | – | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Promethazine | Antihistaminica | – | – | – | – | JA | – | – | – | – | – | – | – | ||||||||||||
| Propafenon | Anti-aritmica | JA | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Propranolol | Beta-blokkers | JA | – | – | JA | JA | JA | – | – | – | – | – | – | ||||||||||||
| Quetiapine | Psychofarmaca | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Rabeprazol | Maagzuurremmers | – | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Repaglinide | Bloedglucose verlagende middelen | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Riluzol | Overig | JA | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Risperidon | Psychofarmaca | – | – | – | – | JA | JA | – | – | – | – | – | – | ||||||||||||
| Rivaroxaban | Antitrombotica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Ropivacaïne | Anesthetica | JA | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Rosuvastatine | Antilipaemica | – | – | – | – | – | – | – | – | – | – | JA | – | ||||||||||||
| Rufinamide | Anti-epileptica | – | – | – | – | – | – | – | – | – | – | – | – | ||||||||||||
| Salmerterol | Sympathicomimetica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Saquinavir | Antivirale middelen | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Siponimod | Immunomodulantia | – | – | JA | – | – | – | – | – | – | – | – | – | ||||||||||||
| Sertraline | Psychofarmaca | – | JA | JA | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Sildenafil | Urologische middelen | – | – | JA | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Simvastatine | Antilipaemica | – | – | – | – | – | JA | – | – | – | – | JA | – | ||||||||||||
| Sirolimus | Immunomodulantia | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Solifenacine | Urologische middelen | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Sorafenib | Oncolytica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Stiripentol | Anti-epileptica | JA | – | – | JA | – | JA | – | – | – | – | – | – | ||||||||||||
| Sunitinib | Oncolytica | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Tacrolimus | Immunomodulantia | – | – | – | – | – | JA | JA | – | – | – | – | – | ||||||||||||
| Tamoxifen | Oncolytica | – | – | JA | JA | JA | JA | – | – | – | – | – | – | ||||||||||||
| Temsirolimus | Immunomodulantia | – | – | – | – | – | JA | – | – | – | – | – | – | ||||||||||||
| Teniposide | Oncolytica | – | – | – | JA | – | – | – | – | – | – | – | – | ||||||||||||
NB. Aan deze tabel kunnen geen rechten worden ontleend.
Klik hier voor meer achtergrond informatie over farmacogenetica.
